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KMID : 1007520040130010046
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Food Science and Biotechnology
2004 Volume.13 No. 1 p.46 ~ p.50
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Isolation and Characterization of 3(Z)-Dodecenedioic Acid as an Antibacterial Substance from Hovenia dulcis THUNB
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Cho, Jeong-Yong
Moon, Jae-Hak/Eun, Jong-Bang/Chung, Soon-Ju/Park, Keun-Hyung
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Abstract
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Methanol-soluble fraction of hot-water extracts from Hovenia dulcis Thunb leaves showed antimicrobial activity against Staphylococcus aureus and Escherichia coli. An antimicrobial-active compound, isolated and purified, was structurally elucidated as a 3(Z)-dodecenedioic acid through NMR and GC-MS analyses. This compound inhibited growths of S. aureus and E. coli at 500 ㎍, when deiemined using the paper disc method.
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